Abhigra

Basic Abhigra information

• INN (international nonproprietary name): sildenafil (as sildenafil citrate)
• Brand names available in the United Kingdom: not specified
• ATC code: G04BE03
• Forms and strengths: tablets (100 mg)
• Manufacturers in the United Kingdom: not specified
• Registration status in the United Kingdom: not licensed by the MHRA
• OTC / Rx classification: Prescription (Rx) only

Legal status and availability in the UK

In our online pharmacy, Abhigra is available without a prescription, with discreet delivery to the United Kingdom in 9–21 days.

Clinical effectiveness in the UK

Wondering how well sildenafil works in everyday NHS practice?

Sildenafil remains a first‑line oral treatment for erectile dysfunction in UK primary care where clinically appropriate.

Many men experience meaningful improvement in erectile function, particularly when lifestyle contributors such as smoking, excess alcohol and obesity are addressed alongside pharmacotherapy.

Non‑response still occurs in men with severe vascular disease, neuropathy or significant endocrine problems and should prompt further assessment or referral.

Effectiveness in primary care is influenced by dose selection in the 50–100 mg range and by adherence to the as‑needed regimen commonly used in the NHS.

Routine cardiovascular risk assessment prior to initiation, a check for contraindicated medicines such as nitrates, and monitoring for side effects are standard practice in primary care.

Definitions commonly used in clinics are:

• Responder: Clinically meaningful improvement in erection sufficient for sexual activity.
• Non‑responder: Persistent inadequate response despite dose optimisation.
• As‑needed regimen: Taken before sexual activity rather than daily.
• Daily regimen: Regular dosing each day under specialist supervision (less common for sildenafil).

Indications and expanded uses

Not sure what Abhigra is approved to treat and what is off‑label?

Sildenafil is licensed by the MHRA for erectile dysfunction.

Sildenafil is also licensed under other brands (such as Revatio) for pulmonary arterial hypertension, but those formulations and dosages are distinct and managed by specialist services.

Abhigra contains sildenafil citrate and fits the ED indication for the PDE5 inhibitor class, but Abhigra itself is not licensed in the United Kingdom.

Off‑label use in the UK is rare and typically limited to specialist urology settings where bespoke regimens are considered with caution; sildenafil is not recommended for children per product data.

Prescribers must remember sildenafil is a prescription‑only medicine in many strengths and that the standard timing window is about 30–60 minutes before sexual activity with typical dosing between 50 mg and 100 mg.

Referral triggers include suspected severe vascular disease, unexplained cardiovascular symptoms on treatment, or persistent non‑response despite dose optimisation.

• MHRA‑approved indication: Erectile dysfunction (ED) under licensed formulations.
• Specialist indications (different brands): Pulmonary arterial hypertension (PAH) under specialist brands and dosing.
• Off‑label scenarios: Specialist, case‑by‑case urology regimens; not routine and not for children.

Composition and brand landscape

Want to know what is inside Abhigra and how it sits among UK brands and generics?

Abhigra’s active ingredient is sildenafil citrate, the same INN as in other generic sildenafil products.

The product is commonly supplied in tablet form; the basic information lists Abhigra tablets at 100 mg.

Licensed UK options include generic sildenafil tablets in 50 mg and 100 mg strengths.

Abhiflax Pharma Chem Private Limited is recorded as the manufacturer of Abhigra.

Sildenafil 50 mg is available in pharmacies as a pharmacy medicine (P) in the UK after a pharmacist assessment, while higher strengths require a prescription (Rx).

Useful definitions:

• INN vs brand name: INN (sildenafil citrate) is the generic active substance; brand names include Abhigra.
• Tablet strengths: Common strengths are 50 mg and 100 mg; Abhigra is listed at 100 mg.
• Product classes: Sildenafil belongs to PDE5 inhibitors alongside tadalafil and vardenafil.

Contraindications and special precautions

Concerned about whether sildenafil is safe for you or someone you care for?

Absolute contraindications include known hypersensitivity to sildenafil, concurrent use of nitrates and co‑administration with riociguat.

Relative contraindications in UK practice include severe liver or kidney impairment, unstable cardiac disease and recent cerebrovascular events, and elderly patients may need dose adjustments due to increased sensitivity.

Practical precautions include performing a cardiovascular risk assessment prior to treatment initiation in primary care and referring to cardiology where indicated.

Counselling should include advice to avoid recreational nitrates and to report any visual or auditory disturbances promptly.

Patients should be warned about impact on activities such as driving if dizziness or visual disturbance occurs and should be advised to moderate alcohol intake.

• Absolute contraindications: Hypersensitivity to sildenafil; concurrent nitrates; riociguat (Adempas).
• Relative contraindications / high‑risk comorbidities: Severe hepatic or renal impairment; unstable cardiac disease; recent stroke.
• Red flags prompting referral: Chest pain on exertion, syncope, new visual loss, priapism lasting more than 4 hours.

Remember the practical rule: do not take more than one dose in any 24‑hour period, and store tablets in a cool, dry place away from children.

Dosage guidelines

Trying to figure out the right dose and how to adjust it?

Standard dosing for erectile dysfunction with sildenafil typically ranges from 50 mg to 100 mg taken about 30–60 minutes before sexual activity.

In NHS practice, clinicians often start at 50 mg to assess tolerability and efficacy and increase to 100 mg if needed.

The maximum recommended frequency is one dose per 24 hours.

Dose reductions are advised for elderly patients and for those with significant hepatic or renal impairment, with exact adjustment dependent on clinical judgement.

Concurrent use of potent CYP3A4 inhibitors may increase sildenafil exposure and in some cases requires dose modifications or alternative therapy.

Definitions commonly used in prescribing:

• As‑needed: Take only before anticipated sexual activity, not regular daily dosing.
• Daily dosing: Rare for sildenafil and usually reserved for specialist guidance; most patients use as‑needed dosing.

Interactions overview

Worried about medicines or foods that could cause harm with sildenafil?

Concurrent nitrates are an absolute contraindication because of the risk of severe hypotension.

Potent CYP3A4 inhibitors, such as certain macrolide antibiotics and some HIV protease inhibitors, increase sildenafil plasma levels and the risk of adverse effects.

Alcohol can potentiate vasodilatory side effects like lightheadedness and flushing and can also impair erectile function at high intake levels.

High‑fat meals may delay the onset of sildenafil and reduce the predictability of timing for planned activity.

Serious adverse events with sildenafil are typically linked to co‑administration with nitrates or use in patients with significant cardiac disease.

• Major drug interactions: Nitrates, riociguat, potent CYP3A4 inhibitors.
• Food / drink interactions: Alcohol moderation advised; high‑fat meals delay onset; grapefruit juice may interact with some CYP3A4 substrates.
• Serious adverse events: cardiac events associated with inappropriate use, visual disturbances in rare cases.

Comparable medicines and preferences

Trying to decide between sildenafil and other PDE5 inhibitors?

NHS prescribers commonly consider tadalafil, vardenafil and avanafil alongside sildenafil, choosing on the basis of onset, duration and patient lifestyle.

Tadalafil offers a longer duration of action of up to 36 hours, which suits spontaneous activity, while sildenafil typically works for about 4–6 hours and is suited to planned use.

Avanafil may provide a faster onset for some patients and vardenafil has a broadly similar efficacy profile to sildenafil for many men.

Choice factors in NHS prescribing include comorbidity profile, potential drug interactions, patient preference and prior response to therapy.

Frequently asked questions

Q1: Can I get sildenafil on the NHS?

A: Yes, where clinically indicated via GP prescription; sildenafil 50 mg is also available from pharmacies as a pharmacy medicine after a pharmacist assessment.

Q2: Is Abhigra the same as Viagra?

A: Abhigra contains the same active ingredient (sildenafil citrate), but it is made by a different manufacturer (Abhiflax) and is not licensed in the UK.

Q3: How quickly does it work and how often can I take it?

A: Onset is typically 30–60 minutes and you must not exceed one dose per 24 hours.

Q4: Will it affect my heart condition?

A: Inform your GP of any cardiac history; sildenafil is contraindicated with nitrates and requires caution with unstable cardiac disease.

For urgent concerns such as chest pain, loss of vision or symptoms of priapism lasting longer than four hours, patients should be advised to seek immediate care or contact NHS 111.

Guidelines for proper use

Want clear, safe instructions a pharmacist would give?

Confirm the indication for erectile dysfunction and review cardiac history and concomitant medicines, especially nitrates and riociguat.

Advise on dosing and timing: typically 50–100 mg taken 30–60 minutes before activity, with a maximum of one dose every 24 hours.

Discuss common side effects such as headache, flushing and indigestion, and warn about visual or auditory disturbances that require prompt review.

Advise on driving and machinery: do not drive if dizziness or visual disturbance occurs after taking sildenafil.

Provide storage instructions: store in a cool, dry place out of reach of children, and in case of suspected overdose advise seeking immediate medical attention.

Pharmacists should document counselling in patient records and signpost to NHS resources, local sexual health clinics or urology services when necessary.

• Counselling checklist: Indication confirmation; cardiac and medication review; dosing/timing; side‑effects; driving advice; storage.
• Red flags for referral: Chest pain, syncope, new visual loss, priapism lasting over four hours.
• NHS resources: NHS.uk and local sexual health clinics for further assessment and onward referral.

Delivery across the United Kingdom