Viagra With Dapoxetine

Basic Viagra with dapoxetine information

• INN (international nonproprietary name): Sildenafil (a phosphodiesterase type 5 inhibitor) and Dapoxetine (a selective serotonin reuptake inhibitor).
• Brand names: Super P-Force, Sildigra Super Power, Manforce Duralong and generic sildenafil + dapoxetine tablets; Priligy is the stand-alone reference brand for dapoxetine.
• ATC code: the fixed combination does not have a unique WHO ATC code; sildenafil is G04BE03 and dapoxetine is G04BX14.
• Forms and strengths: oral film-coated tablets commonly supplied as 100 mg sildenafil + 60 mg dapoxetine, 50 mg + 30 mg, and 100 mg + 30 mg in blister strips of 4 or 10 tablets.
• Manufacturers: Sunrise Remedies, Fortune Healthcare, Centurion Laboratories and Ajanta Pharma.
• Registration status in the United Kingdom: the fixed sildenafil plus dapoxetine combination is not licensed in the UK.
• OTC / Rx classification: Prescription-only (Rx) and not available over the counter due to safety and interaction risks.

Legal status and availability in the UK

In our online pharmacy, Viagra with dapoxetine is available without a prescription, with discreet delivery to the United Kingdom in 9–21 days.

Clinical effectiveness in the UK

Will men see meaningful benefit from the combination?

Many UK clinicians adopt a stepwise approach: optimise PDE5 dose first and then add dapoxetine if response is inadequate, because the fixed combination lacks a UK licence.

Common starting dose used in practice is sildenafil 100 mg plus dapoxetine 60 mg given on-demand and as a prescription-only medicine.

Effectiveness in routine care depends on cardiovascular screening, mental-health review and checks for drug interactions before prescribing.

Clinicians also consider patient adherence, and discontinuation rates due to nausea or dizziness.

• Outcome measures: International Index of Erectile Function (IIEF) improvement, intravaginal ejaculatory latency time (IELT) increase, and incidence of adverse events.
• Comparison in practice: combination therapy tends to increase IELT more than sildenafil alone while improving erection success compared with dapoxetine alone.

Indications and expanded uses

Who is the right candidate for a combined sildenafil and dapoxetine approach?

Licensed indications in the UK cover sildenafil for erectile dysfunction and dapoxetine for premature ejaculation, but the fixed sildenafil + dapoxetine tablet is not licensed in the UK.

Clinicians may prescribe the combination for adult men with concurrent ED and PE who have failed single-agent therapy, after cardiac and psychiatric assessment.

Off-label or unlicensed use typically occurs in specialist sexual health or private clinics with documented clinical rationale and informed consent.

1. Licensed: a use specifically authorised by a regulator for an identified indication.
2. Unlicensed: a product supplied without a local marketing authorisation, often imported for a valid clinical need.
3. Off-label: use of a licensed medicine for an indication, dose or population not covered by its licence.

Pre-prescription checklist: confirm cardiac history and current nitrates, assess hepatic and renal function, screen for mood disorders and suicidal ideation, and review current medications for interactions.

Avoid prescribing in adolescents and ensure counselling about contraception and partner safety where relevant.

Composition and brand landscape

What exactly is in these tablets and which brands are commonly seen?

The fixed combination contains the INNs sildenafil and dapoxetine, typically film-coated for moisture protection and tolerance.

Brand names include Super P-Force, Sildigra Super Power, Manforce Duralong and various generics marketed as sildenafil dapoxetine tablets.

Typical fixed strengths include 100 mg sildenafil + 60 mg dapoxetine, 50 mg + 30 mg and 100 mg + 30 mg.

Packaging is commonly blister strips of 4 or 10 tablets with batch and dosage information printed.

Storage recommendations: keep in original blister, store at 15–30°C, and protect from moisture and heat.

Contraindications and special precautions

What makes this combination unsafe for some men?

Absolute contraindications include hypersensitivity to either active ingredient, concurrent nitrate therapy, unstable cardiovascular disease and moderate to severe hepatic or renal impairment.

Dapoxetine adds psychiatric cautions such as bipolar disorder, major depression and a history of suicidal ideation.

Relative precautions include elderly patients, those on alpha-blockers or antihypertensives, and people with mild hepatic or renal impairment who require monitoring.

MAOI co-administration is contraindicated without a 14-day washout period.

Advise caution for driving or operating machinery if dizziness or visual disturbance occurs, and warn that alcohol can worsen hypotension and sedation.

• Absolute contraindications: nitrates, recent myocardial infarction or stroke, hypersensitivity to sildenafil or dapoxetine, moderate-severe hepatic or renal impairment.
• Relative contraindications: concomitant alpha-blockers or multiple antihypertensives, elderly patients, and recent MAOI use without washout.

Red-flag symptoms requiring urgent care: erection lasting longer than four hours (priapism), fainting or syncope, sudden severe vision loss, and severe mood change or suicidal thoughts.

Dosage guidelines

How should patients take the medicine safely for best effect?

Usual on-demand dosing in product summaries is sildenafil 100 mg combined with dapoxetine 60 mg taken 1–3 hours before sexual activity.

Lower fixed strengths such as 50 mg + 30 mg or 100 mg + 30 mg are used to improve tolerability in some patients.

The regimen must not be used more than once every 24 hours and is not intended for daily maintenance therapy.

In elderly patients and those with hepatic or renal impairment consider a lower initial dose or closer monitoring, and avoid use in moderate to severe organ dysfunction.

For non-responders, a trial period of up to three to six months with regular review is described in practice guidance.

Always document informed consent when prescribing an unlicensed fixed combination within UK practice.

Interactions overview

Which medicines and substances must be checked before dispensing?

Nitrates are an absolute contraindication due to the risk of severe and potentially life-threatening hypotension when combined with sildenafil.

Potent CYP3A4 inhibitors can raise sildenafil levels and require caution or dose adjustment.

Alpha-blockers and other antihypertensives can have additive blood-pressure lowering effects, increasing orthostatic hypotension risk.

Concomitant serotonergic agents raise the risk of serotonin syndrome when combined with dapoxetine and require careful review.

MAO inhibitors require a 14-day washout before dapoxetine can be used.

Alcohol increases the risk of dizziness, orthostatic effects and sedation and should be limited around the dose.

Pharmacists should perform immediate checks for nitrates, MAOIs and interacting antidepressants as part of standard safety screening.

Comparable medicines and preferences

What are the alternatives and how do they compare?

Alternatives include tadalafil plus dapoxetine and vardenafil plus dapoxetine combinations, and monotherapy options such as sildenafil for ED and dapoxetine for PE where available.

Tadalafil has a longer duration and suits men who prefer spontaneity, while sildenafil is shorter acting and preferred for planned on-demand use.

Common adverse effect profiles vary: tadalafil commonly causes myalgia and back pain, sildenafil can cause visual disturbance and flushing, and dapoxetine commonly causes nausea and transient mood effects.

Choice should be based on desired spontaneity, adverse-effect tolerance, interaction profile and licensing status.

Frequently asked questions

Is the fixed sildenafil plus dapoxetine tablet MHRA-approved?

No. The fixed combination is not MHRA-authorised as a combined product; the components are established medicines, but the combination itself is unlicensed.

Can I take this combination with my blood pressure tablets?

Not without a clinical review because co-prescribing with alpha-blockers or multiple antihypertensives can increase the risk of hypotension and requires assessment.

How often can I take the combination?

The product is intended for on-demand use and should not be taken more than once every 24 hours.

When to seek urgent care?

Seek emergency help for priapism lasting more than four hours, sudden fainting, sudden severe vision loss, or new severe mood changes including suicidal thoughts.

Guidelines for proper use (pharmacist and NHS counselling)

What should a pharmacist discuss before handing over the medicine?

Confirm identity and age, and verify the indication for combined ED and PE treatment.

Review cardiovascular history thoroughly and check for current nitrate or MAOI use.

Ascertain current antidepressant or serotonergic medicines and screen for mood disorders and suicide risk.

Explain dosing: take the tablet 1–3 hours before sexual activity and no more than once every 24 hours.

Counsel about common side effects such as dizziness, nausea and blurred vision and advise standing slowly to reduce orthostatic symptoms.

Explain storage requirements: keep in original blister and store at 15–30°C away from moisture.

Make clear the product’s unlicensed status if applicable, document informed consent and encourage Yellow Card reporting for adverse events.

• Pharmacist checklist for dispensing: identity, nitrates check, antidepressant/MAOI check, hepatic/renal review, dosing and emergency advice, documentation.
• Quick patient leaflet points: expected benefits, common side effects, red-flag symptoms and contact details for urgent care.

Delivery across the United Kingdom